Figure 15-11: Acceptance or rejection of various RNA structure elements introduced in a non-coding region of MS2. At the left we show the wild-type structure, containing the stopcodon (UAG italics) of the maturation gene. Mutant A has been given a big unstructured loop that is almost fully deleted during passaging (double arrows). Mutant C, containing a nearly perfect hairpin extension, is genetically stable for many generations. Mutant R with the perfect hairpin extension is an RNase III substrate. In RNase III-deficient strains the stem is genetically stable but in wild-type E. coli suppressor mutations occur that make the stem RNase III resistant (bold italics top right). We show only some representative examples of the pseudorevertants obtained. (for better image quality, click here for tif image, which may be quite large; may also require screen refreshing plus special software to view; or view larger tif in separate window)

Figure 15-1, Figure 15-2 ( ab ), Figure 15-3, Figure 15-4, Figure 15-5, Figure 15-6, Figure 15-7, Figure 15-8, Figure 15-9 ( ab ), Figure 15-10, Figure 15-11, Figure 15-12, Figure 15-13,

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